Thc & Tropacocaine

Reader's Notice viii Preface viv THC 1 Medical Cannabis 1(12) CANNABIS. U.S. (Br.) CANNABIS Cannab 2(8) THC 10(1) Synhexyl 11(2) 2 Stereochemical Requirements for Cannabimimetic Activity 13(18) 3 Cannabinoid Receptors 31(10) CB2 Agonist Treament of Autoimmunine Disorders 34(1) CB-2 Receptor Agonist Compounds 35(1) Inhibition of Cell Proliforation 36(1) Cannabinoids in the Treatment of Glaucoma 36(1) Anandamide Amidase Inhibitors as Analgesic Agents 37(1) CB1 Agonists for Use in Brain Trauma 38(1) Erratic Gastrointestial Absorbtion of delta-9-Tetrahydrocannabinol 39(1) Treating Mental Diseases, Inflammation and Pain with Anandamides 40(1) 4 Cannabinoid Extraction 41(6) Extraction of Delta-9-Tetrahydrocannabinol from Cannabis 42(1) Extraction of Cannabis Buds (41% THC Oil) 43(1) Extraction of Cannabis Buds 2 (40% THC Oil) 44(1) Direct Fractional Distillation of the Hexane Extract (92% THC Oil) 44(1) Preparing Delta-9-Tetrahydrocannabinol 45(1) Direct Treatment of Cannabis Extracts with Methanolic KOH Solution (70% THC Oil) 45(1) Reprocessing of the Residue Left After Fractional Distillation of Cannabis Extracts (82% THC Yellow Oil) 45(2) 5 THC Syntheses 47(24) Water Soluble Derivatives of Cannabinoids 47(1) Synthesis of Compound (4) Ketones from Nitriles 47(1) NMDA-blocking pharmaceuticals 48(2) THC in the Treatment of Glaucoma in Patients who can not take Beta-blockers 50(1) Compositions useful as a cannabinoid receptor probe 51(1) NMDA-blocking Pharmaceutical Compositions 52(1) Production of 6,12-Dihydro-6-hydroxy-cannabidiol and the use Thereof for the Production of trans-delta-9-Tetrahydrocannabinol 53(3) Production of 6,12-Dihydro-6-hydroxy-cannabidiol 56(1) Production of trans-delta-9-Detrahydrocannabinol 56(1) Preparation of cis-p-Menth-2-ene-1,8,-diol 57(1) Novel Tetrahydrocannabinol Type Compounds 57(2) Preparation of (-)-6a,l0a-trans-6a,7,8,10a- Tetrahydrodibenzo[b,d]-pyrans 59(2) Preparation of Optically Active trans-Hexahydrodibenzopyranones 61(2) 1-Hydroxy-3-(1,1-dimethyleheptyl)-6,6-dimethyl-6,6aR,7,8,10,10aR-hexahydro-9-H-dibenzo[b,d]pyran-9-one 63(1) Producing 6a,10a-trans-6a,7,8,10a-Tetrahydrodibenzo (b,d)-pyrans 64(4) Dibenzo[d,b]pyrans and Process 68(2) 3-(1,2-Dimethylheptyl)-6a,7,10,10a-tetra-hydro-1-hydroxy-6,6,6-trimethyl-6H-dibenzo [b,d]pyran 70(1) 6 5-Alkylresorcinols 71(10) Preparation of 1-Hydroxy-2,6-dimethoxy-4-(tertiary alkyl)benzene 71(1) 1-Hydroxy-2,6-dimethoxy-4-(1,1-dimethylheptyl)benzene 72(1) Divarin Dimethyl Ether from 3,4,5-Trimethoxy-propiophenone 73(1) Reduction of Ketones to Resorcinols 74(1) Synthesis of 5-Alkylresorcinols 74(1) Synthesis of 5-Ethylresorcinol 74(1) Preparation of Hexylresorcinol by Electrolytic Reduction of Hexanoylresorcinol 74(1) Synthesis of 5-Methylresorcinol (Orcinol) 75(1) 5-Alkylresorcinol from Demethylation of 1-(Alkyl)-3,5-Dimethoxybenzene 75(1) Demethylation Using Pyridine 5-(1,1-dimethylheptyl)resorcinol 76(1) Demethylation Using 48% Hydrobromic Acid 5-(1,1-Dimethylheptyl)resorcinol 76(1) Preparation of 5-Alkoxyresorcinols 77(1) Preparation of Phloroglucinol and its Mono-ethers 78(3) Preparation of Compounds with Marijuana Activity 81(1) Formation of Tetrahydrocannabinols by Isomerization of Cannabidiol 82 A. By p-toluenesulfonic acid 82(1) B. By sulfuric acid 83(1) C. By pyridine hydrochloride 83(1) D. By phosphoric acid 83(1) E. Sulfamic acid; zinc chloride 84 7 Isomerisation 81(10) Converting cis-Hexahydrodibenzo[b,d]pyran-9-ones to trans-Hexahydrodibenzo[b,d]-pyran-9-ones 85(1) dl-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a, 7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one 86(1) dl-trans-1-Hydroxy-3-n-pentyl-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one 87(1) dl-trans-1-Hydroxy-3-(1,1-dimethyl heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one 87(1) Stereos elective Preparation of Hexahydro dibenzopyranones and intermediates therefor 88(1) (-)-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one 88(1) Acetylation of THC 89(2) 8 Delta 1-THC-7-oic acid Analgesic and Anti-inflammatory Agents 91(8) Platelet Activating Factor Antagonist 95(2) Non-psychoactive Derivatives of &Detla;6-THC-7-oic Acid which have Analgesic and Anti-inflammatory Properties 97(1) Synthesis of (3R,4R)-Δ6-THC-DMH-7-oic Acid Acetate 97(2) 9 Andanamides: Fatty Acid Amides 99(12) Preparation of Arachidonyl Ethanolamide 101(2) Compounds Isolated from the Brain and Synthesized 103(1) Synthetic Compounds Prepared and Tested 103(1) Anandamide Amidase Inhibitors as Analgesic Agents 104(2) Treating Anxiety and Mood Disorders with Oleamide 106(2) Oleamide 108(3) 10 Fatty Acid Amides Preparation from Common Household Oils 111(8) Preparation of Oleamide 111(1) The Reactions Used 111(1) N-Substituted Amides of Natural Fatty Acids 112(1) Preparation of N-Methyl Linseed Oil Fatty Acid Amide 113(1) Preparation of N-Cyclohexyl Linseed Oil Fatty Acid Amide 113(1) Preparation of Lauric Diethanolamide from Lauroyl Chloride 114(1) Preparation of Cocoa Fatty Acid Amide Using the Aminolysis Method 115(1) Industrial Manufacture of Fatty Acid Ethanolamides 115(1) Preparation of Oleic Acid Monoethanolamide 116(1) Purification of Fatty Acid Amides Using Urea 117(1) Preparation of Olive Oil and Coconut Oil Ethanolamides 117(1) Preparation of Fatty Acids 118(1) Isolation of Linoleic Acid 118(1) Isolation of Oleic Acid from Olive Oil 118(1) Production of Monoalkyolamines 118(1) TROPACOCAINE 1 Coca, The Source of Cocaine 119(8) Coca 122(5) 2 Cocaine 127(14) COCAINA. U.S., Br. 131(3) COCAINE HYDROCHLORIDUM. U.S., Br. 134(7) 3 Atropine and the Tropeines 141(6) Cocaine and the Local Anesthetics 143(4) 4 Tropacocaine 147(10) Tropacocaine 148(1) Benzoyl Ester of Ecgonine Using Benzoic Anhydride 149(1) Tropacocaine from Pseudo-tropine & Benzoic Anhydride 149(2) Pseudotropine by Electrolytic Reduction of Tropine 151(1) Tropineone by Oxidation of Tropine 151(1) Extraction of Pseudotropine 152(1) Pseudotropine by the Electrolytic Reduction of Tropinone 152(1) Tropinone by the Oxydation of Tropine 152(1) Tropinone by the Oxydation of Pseudotropine 152(1) Tropinone by the Electrolytic Reduction of Tropine or Pseudotropine 153(1) Benzoic Anhydride 153(4) 5 Narcotic Daturas 157(8) Origin of the Name Jimson, or Jamestown Weed 159(2) The Huaca-Cachu of Peru 161(4) 6 Datura Alkaloids 165(4) Hyoscyamine and Atropine 165(1) Atropine Sulphate 166(1) Hyoscine or Scopolamine 167(1) Extraction of Atropine 167(2) 7 Growing Datura and Related Species 169(8) BELLADONNA Atropa belladonna 169(2) Atropa belladonna (Belladonna) Cultivation 171(2) Datura stramonium L. (Jimson Weed) 173(1) Datura stramonium (Jimson weed) Cultivation 174(1) Hyoscyamus niger (Henbane) Cultivation 175(1) Solanum nigram L. (Black Nightshade) 176(1) Suggested Reading 177(1) Bibliography 177