Transplantation of Neural Tissue into the Spinal Cord

Preface ix Anatomy and Physiology of the Spinal Cord 1(23) Antal Nogradi Gerta Vrbova Anatomy of the Spinal Cord 1(8) Function of the Spinal Cord 9(9) Neurotransmitters and Receptors in the Spinal Cord 18(6) Recovery of Function After Spinal Cord Injury 24(28) Gavin Clowry Urszula Slawinska The Effect of Spinal Transection on Behavior during Postnatal Development of the Rat and Kitten 31(2) The Capacity of Spared Pathways for Sprouting Following Partial Injuries 33(3) The Effect of Lesions to the Developing Mammalian Spinal Cord on the Neurons Innervating It 36(6) Discussion: Possible Substrates for Recovery of Function After Injury 42(10) Recovery of Lost Spinal Cord Function by Facilitating the Spinal Cord Circuits Below the Lesion 52(15) Urszula Slawinska Spinal Cord Functions Controlled by Brain Stem Monoaminergic Connections 52(3) Intraspinal Transplantation of Neural Cells of Supraspinal Origin 55(12) Encouraging Regeneration of Host Neurons: The Use of Peripheral Nerve Bridges, Glial Cells or Biomaterials 67(22) Antal Nogradi Grafting Peripheral Nerves into the Spinal Cord 68(5) Transplantation of Schwann Cells and Olfactory Ensheathing Cells into Lesioned Spinal Cord to Enhance Regeneration 73(6) Implantation of Various Materials into the Spinal Cord 79(10) Encouraging Regeneration of Host Neurons: Transplantation of Neural Tissues into the Injured Spinal Cord Grafts of Embryonic Neural Tissue 89(21) Gerta Vrbova Survival and Development of Embryonic Grafts in the Spinal Cord 90(5) Integration of the Grafted Tissue with the Host Spinal Cord 95(6) Graft-Induced Improvement of Function 101(3) The Use of Other Cell Types to Promote Recovery After Spinal Cord Lesion 104(6) Replacement of Specific Neuronal Populations in the Spinal Cord 110(13) Antal Nogradi Conditions for Survival of Transplanted Embryonic Motoneurones 111(2) Transplantation of Embryonic Motoneurones into the Adult Spinal Cord 113(6) Transplantation of Embryonic Motoneurones into the Spinal Cord of Immature Animals 119(1) Most Important Points 120(3) Replacement of Specific Populations of Cells: Glial Cell Transplantation into the Spinal Cord 123(22) Antal Nogradi Transplantation of Schwann Cells 124(4) Transplantation of Olfactory Ensheathing Cells 128(1) Transplantation of Oligodendrocytes 129(6) Transplantation of Astrocytes 135(1) Migration and Effects of Grafted Astrocytes 135(2) Transplantation of Macrophages into the Injured Spinal Cord 137(8) Conclusion 145(2) Index 147