SECTION I. <br>ETIOLOGY AND INITIAL EVALUATION OF THE PATIENT WITH CHRONIC VENOUS INSUFFICIENCY<br>Inflammation and the Pathophysiology of Chronic Venous Disease: Molecular Mechanisms <br>Microcirculation in Chronic Venous Insufficiency<br>Epidemiology of Venous Ulcers<br>Lower Extremity Ultrasound Evaluation and Mapping for evaluation of chronic venous disease<br>Hypercoagulable States Associated with Chronic Venous Insufficiency<br>The Chronically Swollen Leg: Finding the Cause - Theory and Practice<br>SECTION II.<br>NON-OPERATIVE MANAGEMENT OF CHRONIC VENOUS INSUFFICIENCY<br>Compression Therapy of Chronic Venous Insufficiency <br>Wound Healing Adjuvant Therapy and Treatment Adherence<br>Negative Pressure Dressings in Venous Ulcers<br>Deep Venous Thrombosis and Prevention of the Post-Thrombotic Syndrome<br>SECTION III.<br>THERAPUTIC PROCEDURES FOR CHRONIC VENOUS INSUFFICIENCY<br>Results Comparing Compression Alone vs. Compression and Surgery in Treating Venous Ulceration<br>Superficial Surgery and Perforator Interruption in the Treatment of Venous Leg Ulcers<br>Endovascular Techniques for Superficial Vein Ablation in Treatment of Venous Ulcers<br>Treatment of Chronic Venous Insufficiency with Foam Sclerotherapy<br>Foam Treatment of Venous Leg Ulcers, the Initial Experience<br>Foam Treatment of Venous Leg Ulcers, a Continuing Experience<br>Ultrasound Guidance for Endovenous Treatment<br>Repair of Venous Valves in Severe Chronic Venous Insufficiency <br>SECTION IV.<br>SPECIAL TOPICS<br>Treatment of venous and combined ulcers with free tissue transfer for limb salvage<br>Diagnosis and Treatment of Major Venous Obstruction in Chronic Venous Insufficiency<br>The Venous Ulcer and Arterial Insufficiency<br>Topical negative pressure techniques in chronic leg ulcers <br>A Treatment Algorithm for Venous Ulcer: Current Guidelines<br>EPILOGUE