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Translating Regenerative Medicine to the Clinic

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2015
ISBN13: 9780128005484
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Juridisch :
Elsevier Science e druk, 2015 9780128005484
€ 112,54
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Samenvatting

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin.

Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic.

Specificaties

ISBN13:9780128005484
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

Introduction: Regenerative Medicine for Cardiovascular Disease-A Good Start <br>PART I: STEM CELLS:  <br>Chapter 1: Introduction and Overview of Stem Cells<br>Chapter 2: Mechanistic Insights from Pathologic Perspective <br>Chapter 3: Large Animal Models to Study Stem Cell Therapy<br>Section I. Body’s Native Repair Mechanisms<br>Chapter 4. Evolution of understanding of the mechanisms of repair     <br>Chapter 5: Impact of Age on Stem Cell Function<br>Section II: Autologous Bone Marrow<br>Chapter 6: Bone Marrow Mononuclear Cells<br>Chapter 7: Chronic Limb Ischemia<br>Chapter 8: Chronic/Refractory Angina<br>Chapter 9: Acute Myocardial Infarction<br>A. European Experience:  Andreas Zeiher<br>B. US Experience: Jay Traverse <br>Chapter 10: Chronic Ischemic Heart Failure<br>Section III:  Autologous Adipose Derived Regenerative Cells<br>Chapter 11: Adipose Tissue<br>Section IV: Allogeneic Alternatives to Autologous Bone Marrow<br>Chapter 12: Overview of MSCs     <br>Chapter 13: Allogeneic vs Autologous Source: Comparative Effects<br>Chapter 14: Use of MSCs for AMI<br>Chapter 15: Combined Cell Strategies<br>Chapter 16: Heart Failure<br>Section V: Cardiac Progenitor Cells<br>Chapter 17:  C-Kit+ cells<br>Chapter 18:  Cardiospheres<br>Section VI: Other Allogeneic Sources of Stem Cells<br>Chapter 19:  Umbilical Cord, Placenta, Endometrium<br>Section VII. Genetic Engineering/Cell Transformation<br>Chapter 20:  Genetic Engineering of Fibroblasts to Cardiomyocytes<br>Chapter 21:  Transformation to inducible Pleuripotent Stem Cells<br>Chapter 22:  Transformation to MAPC's<br>Section VIII: METHODS OF DELIVERY:  <br>Chapter 23.  Transcoronary and Endocardial<br>Chapter 24.  Retrograde and Epicardial<br>Part II. TISSUE ENGINEERING:<br>Chapter 25.  Epicardial Patch<br>Chapter 26.  Matrix Scaffolds<br>Chapter 27.  Matrix plus cells<br>Chapter 28.  Biomaterial<br>Chapter 29:  Organogenesis<br>Part III. GENE THERAPY: <br>Chapter 30:  Pre-clinical Identification of target genes<br>Chapter 31:  SERCA-2a gene for recovery of inotropic function<br>Chapter 32:  SDF-1 Gene for Heart Failure Non-Inotropic Mechanisms<br>Chapter 33:  Gene Therapy for Angiogenesis: Chronic Limb Ischemia <br>Chapter 34:  Stem Cells Target Gene Transfected Stem Cells<br>Part IV: FUTURE DIRECTIONS:<br>Chapter 35:  CCTRN: Past, Present, and Vision for the Future<br>Chapter 36:  Signature of Responders-lessons from Bio-Repository<br>Chapter 37:  Adjunctive therapy with LVADs for Recovery<br>Chapter 38:  Trials in Non-Ischemic Heart Failure  <br>Chapter 39:  Enhancing Stem Cell Homing for Tissue Repair<br>Chapter 40:  Stroke: Pre-Clinical and Clinical Trial Data<br>SUMMARY

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