I. Transport Mechanisms in the Microcirculation.- 1. Capillary Transport and Exchange.- 1.1. Introduction.- 1.2. Endothelia and Epithelia.- 1.3. Fractional Equilibration of Small Solutes during Transcapillary Passage.- 1.4. Analytical Approaches to Tracer Exchange.- 1.5. An Osmotic Weight Transient Model for Estimation of Capillary Transport Parameters in Myocardium.- 1.6. Fluid and Solute Flow across the Walls of Single Capillaries in the Frog Mesentery.- 1.7. The Extravascular Turnover Rate Constant Estimated from Single Circulation Tracer Dilution Curves as an Index of Cellular Transport.- 1.8. Effect of the Red Cell Membrane on the Exchange of Materials in the Microcirculation.- 1.9. Interaction of Aqueous and Lipid Pathways in the Pulmonary Endothelium.- 1.10. Capillary Permeability in Some Pathophysiological States.- 2. Molecular and Oxygen Transport.- 2.1. Permeability of Arterial Capillary Endothelium.- 2.2. Serial Barriers to Blood—Tissue Transport in the Cat Salivary Gland Using Single-Passage Multiple Tracer Dilution.- 2.3. A Theoretical Investigation of Fluid Exchange in a Microoccluded Capillary with Axial Variation of Filtration Parameters.- 2.4. Effect of Hyaluronidase on Transcapillary Fluid and Solute Exchange in the Isolated Dog Hindlimb.- 2.5. Transmembrane Ion Transport in Autoperfused Cat Mesentery.- 2.6. Evidence of an Interference in Oxygen Exchange from Erythrocytes to Tissues in Hypertriglyceridemia.- 2.7. O2 Transport in the Homogeneous and the Inhomogeneous Microcirculation.- 2.8. Effect of Elevated Venous Pressure on Intestinal Oxygen Extraction.- 2.9. Effects of Mechanically Increasing Venous Pressure in the Canine Forelimb on Protein Transport during the Local Administration of Histamine and Acetylcholine.- 2.10. Quantitative Measurement of Macromolecular Transport in Mesenteric Membrane.- 2.11. Effect of Histamine on Microvascular Macromolecular Transport.- 2.12. Regulation of Plasma and Interstitial Albumin: A Theoretical Analysis.- 2.13. Transmural Mass Transfer in the Unsteady Microcirculation.- 2.14. Transport of Solutes across the Intact Rat Diaphragm.- 2.15. Albumin Permeability of the Renal Peritubular Capillary: The PS Product.- II. Microcirculation in Disease States.- 3. Effect of Shock on Capillary Transport.- 3.1. Transport of Small Molecules.- 3.2. Bidirectional Capillary Transport of Small Molecules.- 3.3. Oxygen Transport in Shock.- 3.4. The Low Flow State Predisposition of the Venous Microvasculature.- 3.5. Tissue—Blood Transport and Metabolism in Canine Adipose Tissue during Hemorrhage and Shock.- 4. Shock and Microcirculation.- 4.1. Special Features of Disorders of Microcirculation and Transcapillary Exchange during Experimental Shock.- 4.2. Regional Blood Flow following Traumatic Shock.- 4.3. Hemodynamic Response of the Terminal Vasculature in Different Species during Reversible and Irreversible Hemorrhagic Shock.- 4.4. Energy Factors and Insulin Resistance in Hemorrhagic Shock.- 4.5. Quantitation of White Cell Sticking in Hemorrhagic Shock.- 4.6. Microvascular Response to Hemorrhage in the Rat during Nitrous Oxide (N2O) Relaxant Anesthesia.- 4.7. Microcirculation in the Pathophysiology of Endotoxin Shock.- 4.8. Endotoxin-Induced Microcirculatory Disturbances.- 4.9. Role of Skeletal Muscle Venules in the Response to Endotoxin Shock.- 4.10. The Microcirculatory Response to Shock Lung Factor.- 4.11. The Microcirculation in Cardiopulmonary Resuscitation.- 4.12. Effects of Prostaglandins in Endotoxin Shock.- 4.13. Microcirculatory Approach to the Treatment of Shock Using a New Analogue of Vasopressin.- 4.14. Effects of Synthetic Glucocorticoids on Shock-Induced Alterations in Cyclic Nucleotide Metabolism and Lysosomal Enzyme Release.- 5. Hypoperfusion, Ischemia, and Graft Rejection.- 5.1. Interstitial Tissue Barrier during Low Flow: Its Correction by Hyaluronidase.- 5.2. Endonasal Granulomata and Hypoperfusion.- 5.3. Factors Influencing Responses of Single Arterioles to Occlusion.- 5.4. Redistribution of Blood Flow during Cooling and after Total Circulatory Arrest with Profound Hypothermia.- 5.5. Blood Gas Analysis as an Aid in Assessing the Microcirculation in the Ischemic Limb.- 5.6. Microcirculatory Reactions to Controlled Ischemia: AVital Microscopic Study of Hamster Cheek Pouch.- 5.7. Microvascular Elements of Xenograft Lung Rejection..- 5.8. Microangiography of Rejected Human Kidney Transplants.- 5.9. The Role of Vasospasm in Experimental Renal Xenograft Rejection.- 5.10. Progressive Microvascular Obliteration during Canine Renal Allograft Rejection.- 6. Trauma and Inflammation.- 6.1. A Model of Peripheral Vascular Disease and Assessment of Wound Healing by Angiographic and Nuclear Medicine Techniques.- 6.2. Pathology of the Capillary Wall: Diagnosis and Therapy.- 6.3. Potential Role of Prostaglandins in Modulating Vascular Permeability Changes during Inflammation through Local Alterations in Blood Flow (Hyperemia).- 6.4. An in Vivo Quantitative Evaluation of Radiation Damage and Repair to Microcirculation.- 6.5. Electron Microscopic Findings in the Micro vessel Wall Affected by Venom of the Snake Trimeresurus flavoviridis.- 6.6. In Vivo Skin Capillary Abnormalities in Vinyl Chloride Workers.- 6.7. Vascular Function in a Hamster Cervical Carcinoma following X-Irradiation.- 6.8. Role of Tissue Fluid Hyperosmolality: The Pathogenesis of Posttraumatic Fluid Loss.- 6.9. Albumin Compartmental Changes Secondary to Sepsis.- 6.10. Elevation of Plasma Lysosomal Enzyme Levels after Trauma in Association with Impairment of Hepatic Reticuloendothelial Function.- 6.11. Fibrinolytic Activity in the Lungs following Trauma.- 6.12. Platelet Function and Severe Head Injury.- 6.13. Disseminated Intravascular Coagulation and Head Injury.- 7. Diabetic Angiopathy.- 7.1. Diabetic Nephropathy: Form and Function.- 7.2. The Problem of Tissue Oxygenation in Diabetes Mellitus as Related to the Development of Diabetic Angiopathy.- 7.3 The Morphology of Angiopathy.- 7.4. The Chemistry of Angiopathy.- 7.5. Comments.- 8. Diabetes and Microcirculation.- 8.1. Hemorheological Changes in Diabetes Mellitus.- 8.2. Quantitative Studies of von Willebrand Factor (VWF) in Normal and Diabetic Subjects: Role of VWF in Second-Phase Platelet Aggregation.- 8.3. Capillaries of Israeli Diabetics: I.- 8.4. Cutaneous Microangiopathy in Prediabetes, Chemical Diabetes, and Overt Diabetes.- 8.5. Microscars: A Manifestation of Diabetic Microangiopathy.- 8.6. Quantitative Studies of the Retinal Circulation in Juvenile Diabetic Retinopathy.- 8.7. Abnormal Red Cell Aggregation in Diabetic Retinopathy.- 8.8. Insulin Response in Patients on Intravenous Hyperalimentation.- 8.9. Osmolality of Hyperalimentation Solution in Superior Vena Cava.- 8.10. Effect of Aprotinin on the Pancreas of the Rat after Temporary Ischemia: Light and Electron Microscopic Investigations.- 8.11. Diabetic Retinopathy: A Challenge to Treatment.- 9. Tumors, Cancer, and Muscular Dystrophy.- 9.1. Laser-Induced Microvascular Injury and Tumor-Cell Lodgement.- 9.2. Effects of Epinephrine on Increasing Arterial Perfusion of Experimental Liver Metastases.- 9.3. Changes in Intrahepatic Tumor Circulation Due to Increasing Tumor Growth.- 9.4. Unusual Localization of Kaposi’s Sarcoma with Histological and Electron Microscopic Findings.- 9.5. Alterations in the Microvasculature of Various Tissues in Murine Muscular Dystrophy.- 10. Blood Pressure and Hypertension.- 10.1. Ultrastructure of Arteriolar Nephropathy in Hypertension.- 10.2. Microvascular Characteristics in the Renovascular Hypertensive Rat.- 10.3. Elastosis of Renal Arterioles in Hypertension.- 10.4. On the Nature of Human Activatable Renin.- 10.5. Effects of Acute Hypertension on Pial Microcirculation in Rats.- 10.6. Microvascular Effects of Propranolol in the Spontaneously Hypertensive Rat.- 10.7. Inhibition of Actions of the Fungal Protease Brinolase on the Vasopeptide (Kinin) System.- 10.8. Kininogen and Kininase Activity in Patients with Acute Myocardial Infarction.