Epigenetic Regulation of Lymphocyte Development

Name: Epigenetic Regulation of Lymphocyte Development
Author: Cornelis Murre

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Gebonden, 194 blz. | Engels

Springer Berlin Heidelberg | 2012e druk, 2012

ISBN13: 9783642241024

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Springer Berlin Heidelberg 2012e druk, 2012 9783642241024

Onderdeel van serie Current Topics in Microbiology and Immunology

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The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.

Specificaties

ISBN13:9783642241024

Taal:Engels

Bindwijze:gebonden

Aantal pagina's:194

Uitgever:Springer Berlin Heidelberg

Druk:2012

Serie:Current Topics in Microbiology and Immunology

Inhoudsopgave

<p>Preface.- Roles of lineage-determining transcription factors in establishing open chromatin – lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.- Subject Index</p>

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