Modulation of Presynaptic Calcium Channels

<p>Foreword: Gary Stephens</p><p>Overview</p><p>1. Spatial and temporal regulation of Ca²⁺ channels; Sumiko Mochida </p><p>Interaction partners of calcium channels</p><p>2. Neuronal functions of auxiliary calcium channel subunits; Gerald Obermair and Bernd Flucher </p><p><p>3. Reciprocal regulation of neuronal calcium channels by synaptic proteins; Norbert Weiss and Gerald Zamponi </p><p><p>4. Molecular architecture of Ca²⁺ channel complexes organized by β subunits in presynaptic active zones; Akito Nakao, Mitsuru Hirano, Yoshinori Takada, Shigeki Kiyonaka and Yasuo Mori </p><p><p>5. Control of Ca_V2 calcium channels and neurosecretion by heterotrimeric G protein coupled receptors; Mark L. Jewell and Kevin P.M. Currie </p><p><p>6. Regulation of Ca_V2 channels by small GTPases; Pierre Charnet, Frédérique Scamps, Matthieu Rousset, Claudine Menard, Michel Bellis and Thierry Cens </p><p>7. Protein interaction partners of Ca_v2.3 R-type voltage-gated calcium channels; Maxine Dibué, Etienne E. Tevoufouet, Andreas Krieger, Alexandra Kiel, Dimitar Evdokimov, Thomas Galetin, Serdar Alpdogan, Isha Akhtar, Sabrina Scharf, Renate Clemens, Kayalvizhi Radhakrishnan, Jürgen Hescheler, Toni Schneider, Marcel A. Kamp</p><p>8. Voltage-gated calcium channel signaling to the nucleus; Michel Bellis, Thierry Cens, Claudine Menard, Pierre Charnet and Matthieu Rousset </p><p></p>Mechanisms of studying calcium channel effects<p><p>9. Presynaptic Ca²⁺ influx and its modulation at auditory calyceal terminals; Holger Taschenberger, Kun-Han Lin and Shuwen Chang </p><p><p>10. Use of synthetic Ca²⁺ channel peptides to study presynaptic function; Giovanna Bucci, Sumiko Mochida and Gary Stephens </p><p>Calcium channel therapeutics</p><p>11. Impact of a loss-of-function P/Q type Ca²⁺ channel mutation on excitatory synaptic control of cerebellar Purkinje neurons; David Friel </p><p><p>12. Ca_V2.1 (P/Q) voltage activated Ca²⁺ channels and synaptic transmission in genetic and autoimmune diseases; Osvaldo Uchitel </p><p><p>13. Splicing and editing to customize Ca_V channel structures for optimal neural function; Hua Huang, Juejin Wang and Tuck Wah Soong</p><p><p>14. Presynaptic calcium channels as drug targets for pain; Edward Stevens and Peter Fox</p><p>15. Sensory pathway modulation by calcium channel a₂d₁ subunit; Chunyi Zhou and Z. David Luo </p><p>Index</p>