Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

<p>1. An introduction to adherens junctions: from molecular mechanisms to tissue development and disease; Tony Harris</p><p>Part I: How AJs evolved<br>2. Evolution of the cadherin-catenin complex; Hiroki Oda</p><p>Part II: How cadherins and catenins interact to assemble AJs<br>3. The three-dimensional structure of the cadherin-catenin complex; Noboru Ishiyama and Mitsuhiko Ikura<br>4. Biophysics of cadherin adhesion; Deborah Leckband and Sanjeevi Sivasankar<br>5. Adherens junction assembly; Sergey Troyanovski</p><p>Part III: How AJs interface with other cellular machinery<br>6. The cytoskeleton and classical cadherin adhesions; Siew Ping Han and Alpha Yap<br>7. Immunoglobulin superfamily receptors and adherens junctions; Yohei Shimono, Yoshiyuki Rikitake, Kenji Mandai, Masahiro Mori and Yoshimi Takai<br>8. Signaling from the adherens junction; Abbye McEwen, David Escobar and Cara Gottardi<br>9. Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling; Benjamin Nanes and Andrew Kowalczyk</p><p>Part IV: How AJs affect cell behaviour and multicellular development<br>10. Adherens junctions during cell migration; Sandrine Etienne-Manneville<br>11. Adherens junctions and cadherins in Drosophila development; Annalisa Letizia and Marta Llimargas<br>12. Adherens junctions in C. elegans embryonic morphogenesis; Stephen Armenti and Jeremy Nance<br>13. Cadherin function during Xenopus gastrulation; Rudolf Winklbauer<br>14. Adherens junctions in mammalian development, homeostasis and disease: lessons from mice; Barbara Boggetti and Carien Niessen</p><p>Part V: How AJs affect tissue homeostasis and disease<br>15. Adherens junctions and stem cells; Terry Lechler<br>16. Adherens junctions and cancer; Valeri Vasioukhin<br>17. Adherens junctions and pathogens entry; Georgios Nikitas and Pascale Cossart</p><p>Index</p>