Brain Oncology Biology, diagnosis and therapy

I: Oncogenesis.- Genetics of Neuroepithelial Brain Tumours.- Oncogenes, Growth Factors and the Pathogenesis of Human Glioma: The 1986 Engelhardt Lecture.- Amplification and Expression of Viral Sequences and Oncogenes in Human Brain Tumors.- Chromosomal Studies in Malignant Gliomas.- Karyotype Patterns in Forty Human Meningiomas.- II: Neuropathology.- Immunohistochemistry in Neuro-Oncology: Markers or Signposts?.- Immunocytochemistry and the Pathological Diagnosis of Cerebral Tumours.- GFAP Immunoreactivity of Oligoastrocytomas; Study of 120 Cases.- GFA and S-100 Proteins in Low Grade Astrocytomas.- Intermediate Filaments in Fresh Frozen Tissue in Neuro-Oncology; about a Series of 1000 Peroperative Biopsies.- Glutamine Synthetase, a Marker of an Astroglial Subpopulation in Mouse Brain.- Correlation of in Situ Cell Kinetics and Degree of Anaplasia in Human Brain Tumors: Identification of S-Phase Cells with Anti-BUdR Antibodies.- Pronostic Value of Labeling Index in Stereotactic Biopsies of Glial Tumours.- Proliferative Potential of Malignant and Non-Malignant Meningiomas.- Histological Patterns in Germ Cell Tumors.- Dysontogenetic Brain Tumours; Morphological Variability and Problems of Classification.- Congenital Intracranial Tumors.- Meningiomas: The Value of Diagnostic Cytology by Tissue Imprints.- III: Tumoral Immunobiology and Oncobiology.- Modulation of Class I and Class II Major Histocompatibility Complex Antigens in Gliomas.- Isolation, Functional Properties and Clonal Analysis of Tumor-Infiltrating Lymphocytes from Human Brain Tumors.- The Applications of Monoclonal Antibodies in Neuro-Oncology.- In-Vivo-Localization of Radiolabelled Monoclonal Antibody in Human Gliomas.- Levels of Polyamine Biosynthetic Decarboxylase Activities as Indicators of the Degree of Malignancy of Human Primary Central Nervous System Tumors.- Red Blood Cell Polyamines in the Long Term Follow-up of Malignant Gliomas.- The Selective Release of Polypeptides from Human Glioma Cell Cultures and their Modification by Dexamethasone.- Preliminary Assessment of the Correlation between Clinicopathological Features of Intracranial Tumours and the Amount of Extractable Angiogenic Activity: High and Low Mr Factors.- Estrogen and Progesterone Receptors in Central Nervous System Tumors.- Steroid Hormone Receptors and Intracranial Tumors.- Steroid Sex Hormones in Non-Pituitary Brain Tumours.- Trials of Hormonal Manipulation of Meningiomas in Vivo and in Vitro.- IV: Biological and Diagnostic Imaging.- Metabolic Studies of Brain Tumours by Positron Emission Tomography.- Study of 11 C-L-Methionine Uptake in Brain Gliomas by Positron Emission Tomography: Metabolic Grading, and Effects of Radiotherapy and Intra-Arterial Chemotherapy.- Positron Emission Tomography with 11-C-Methionine of Intracranial Tumours Compared with Histology of Multiple Biopsies.- Neuropathology and Regional Imaging of Microcirculation, Tissue pH, Metabolites and Necroses in Cerebral RG2 and F98 Anaplastic Rat Glioma Transplantation Tumors.- Can Polyamines Act as Positron Emitters in Cerebral Oncology? Preliminary Results Obtained in Nude Mice Bearing Human Glioblastoma Xenografts.- Conception and Evaluation of a MRI and CT Stereotactic Frame in Neuro-Oncology.- MRI and the Surgical Treatment of Low Grade Gliomas.- Brain Electrical Activity Mapping in Brain Tumors.- Tumour: An Expert System for the Diagnosis of Brain Tumours in Computer Tomographic Images and Histopathologically.- V: Clinico-Pathological Studies.- Multi-Centre Epidemiological Study on Primary Cerebral Tumours in the Veneto Region. Preliminary Data from June 1st 1985 to December 31st 1985.- Chemically Induced Human Gliomas. Occurence of Brain Gliomas in Three Matchbox Manufacturers. an Occupational Risk?.- Prospective Analysis of Grade III and IV Gliomas, with Considerations on Histological Classification.- Histological Factors in the Prognosis of Malignant Gliomas.- Supra-Tentorial Gliomas: Multivariate Analysis of Prognostic Factors.- High Graded Astrocytoma: Results of Treatment.- Primary Malignant Non Hodgkin’s Lymphomas of the Central Nervous System. Report of Two Cases with a Predominant Callosal Localization.- Tumours of the Pineal Region.- Meningeal and Intra-Cerebral Localizations of Kaposi’s Sarcoma in AIDS.- Intra-Cranial Meningiomas with Extra-Cranial Dissemination.- Intra-Cranial Soft Meningiomas: Diagnostic and Therapeutic Study about 33 Cases.- Brain Metastases Revealing Lung Cancer: The Effect of Combined Surgery on Quality and Duration of Survival.- VI: Neurosurgical Procedures and Radiotherapy Trends.- Therapeutic Modalities in Low Grade Gliomas.- Evaluation of Stereotactic Biopsy as an AID for the Management of Supratentorial Tumors.- Intraoperative Ultrasonography in Neurosurgery.- Surgery as Definitive Salvage Therapy for Primary Brain Tumors.- Radiation Therapy in the Treatment of Malignant Supratentorial Gliomas: Current Trends and Prospects. a Review.- Whole Brain Irradiation is Not Necessary for the Treatment of Malignant Supra-Tentorial Gliomas.- Quality of Treatment Response and Survival in Patients with Supra-Tentorial Malignant Gliomas.- Neuropsychologic Impairment in Adults with Brain Tumors after Radiation Therapy.- The Tolerance of Irradiation in Children with Brain Tumour.- Human High-Grade Gliomas Grafted into Nude Mice: A Model System to Compare Radiotherapy Schedules.- Pharmacology of the Hypoxic Cell Radiosensitizers Ro 03–8799 and SR 2508 in Human Gliomas and Brain Tissue.- Antibody-Guided Irradiation Therapy for Cases of Neoplastic Meningitis.- VII: Chemotherapy and Immunotherapy.- An in Vitro Comparative Study of BCNU, VM 26, 5-FU and Ara-A5?p in Treatment of Primary and Secondary CNS-Neoplasms; Potential Clinical Relevance and Clinical Correlations.- Heterogeneity in Chemosensitivity and Acquisition of Drug Resistance in a Murine Model of Glioma.- Assay of Anticancer Drugs in Tissue Culture: The Effect of Cell Kinetics and the Mode of Action of Drugs on the Chemosensitivity of Cultures Derived from Malignant Brain Tumours.- Preclinical Chemosensitivity Studies with Human Gliomas in Nude Mice.- Rat Glioma Follow-Up by In-Vivo 31-Phosphorus Magnetic Resonance Spectroscopy: Activity of Two New Antineoplastic Agents.- 31-P-NMR Spectroscopy in Vivo of Human and Rat Brain Tumors Grafted on Nude Mice.- Blood Brain Barrier Modification and Chemotherapy in Treatment of Malignant Gliomas.- Human Central Nervous System Pharmacology of Antineoplastic Agents: Implications for the Treatment of Brain Tumors.- Intra-Arterial Chemotherapy for Brain Tumors: A Summary of the Ottawa Experience.- Intra-Arterial Chemotherapy Using Extra-Intracranial by-pass for the Treatment of Malignant Gliomas.- Intra-Arterial Chemotherapy with BCNU. Correlations between Tumour Growth and Red Blood Cell Polyamine Levels.- Effects of Intra-Arterially Administered 1,3-bis (2-Chloroethyl)-1-Nitrosurea (BCNU) on the Electroretinogram of the Rabbit. a Study on the Retinal Toxicity of BCNU.- Cerebral Toxicity Following Supraophthalmic Intracarotid Infusion of BCNU: Study of 4 Malignant Gliomas.- Preliminary Experience with Menogaril in the Treatment of Recurrent Glioblastomas.- Chemotherapy in the Management of Pineal Region Germinomas.- The Effectiveness of Chemotherapy in a Case of Childhood Esthesioneuroblastoma.- Renaissance of Intratumoural Chemotherapy.- Chemotherapy of Malignant Supratentorial Gliomas: Achievements and Prospectives.- Early Phase II Study of the Adoptive Immunotherapy of Human Brain Tumors with Lymphokine-Activated Killer (LAK) Cells and Recombinant Interleukin-2 (rIL-2).- Immunotherapy in Recurrent Malignant Brain Tumors.- Index of Keywords.- Authors Index.