, ,

Mitochondria: The Anti- cancer Target for the Third Millennium

Specificaties
Gebonden, 382 blz. | Engels
Springer Netherlands | 2014e druk, 2014
ISBN13: 9789401789837
Rubricering
Juridisch :
Springer Netherlands 2014e druk, 2014 9789401789837
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book will be focused on mitochondria as very promising targets for anti-cancer drugs, yet to be fully exploited. It will contain chapters focused on aspects of basic research as well as on clinical relevance, which will be written by specialists in the field. That the role of mitochondria in human pathologies goes beyond the neoplastic diseases will be documented by a chapter of the role of mitochondria in Friedreich's ataxia.

Specificaties

ISBN13:9789401789837
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:382
Uitgever:Springer Netherlands
Druk:2014

Inhoudsopgave

Preface.- Mitochondrion: A novel center for cancer cell signalling.- Exploiting BH3 mimetics for cancer therapy.- Regulation of mitochondrial function by MicroRNA.- Mitochondrial complex II as a target for anti-cancer drugs.- Exploiting celecoxib in cancer therapy.- Activation of mitochondria-driven pathways by artemisinin and its derivatives.- Vitamin E analogues as prototypic mitochondria-targeting anti-cancer agents.- Targeting mitochondria of cancer cells: Mechanism and compounds.- Targets and strategies for the mitochondrial assault on cancer.- Emerging anti-cancer targets in mitochondria.- Relevance of mitochondrial functions and plasticity in tumor biology.- Crosstalk between p53 and mitochondrial metabolism.- Progression of cardiomyopathy in Friedreich’s ataxia, a mitochondrial disease.- Index.

Net verschenen

Rubrieken

    Personen

      Trefwoorden

        Mitochondria: The Anti- cancer Target for the Third Millennium