Homeostasis - Tumor - Metastasis

Specificaties
Paperback, blz. | Engels
Springer Netherlands | e druk, 2016
ISBN13: 9789402402483
Rubricering
Juridisch :
Springer Netherlands e druk, 2016 9789402402483
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Homeostasis. The health of an organism is influenced by external and internal changes that may lead to the loss of homeostasis. Under healthy conditions organisms compensate these changes.  If compensation fails disease ensues. Attention will be paid to lifestyle, environmental changes, genetic makeup and health system. It will be answered  how lifestyle, environment, genetic makeup and social conditions help to maintain or upset the biological balance  and lead to cancer.
Tumor formation. To understand this process the transfer of intracellular and the pathways of extracellular information (signal transduction) will be reviewed briefly. Loss of cellular balance may lead to cell death (.e.g. apoptosis) or to rapid cell growth of cells leading to tumor formation.
Metastasis. Animal tumor models serve to understand the spread of the primary tumor cells to distant locations of the organism. Different types of tumors and metastases will be reviewed.​

Specificaties

ISBN13:9789402402483
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Netherlands

Inhoudsopgave

<p>Preface<br>1. Homeostasis<br>Chemical basis of biological regulation<br>Definition of homeostasis, allostasis<br>Aqueous internal environment<br>Optimal systems<br>Basic properties of living systems<br>Metabolism and energy production of living systems<br>Contribution of biological membranes to homeostasis<br>Function of the inner environment and its regulated parameters<br>Cellular, tissue and organ homeostasis<br>Dimensions of health<br>Control of processes<br>Levels of bioregulation<br>Regulation of multicellular organisms<br>Major regulatory systems of organisms<br>Regulatory mechanisms: receptors, reflexes<br>Maintaining human homeostasis<br>Evolutionary aspects and types of regeneration<br>Panic syndromes<br>References<br>2. Cell cultures<br>Cell cultivation<br>Cell cultures<br>Establishment of cell cultures<br>Development of primary tumors<br>Growth of cell lines<br>Technical aspects of cell cultivation<br>Sterile work under the laminar flow hood<br>Deep freezing, storage of cells<br>Cell cycle synchronization and its flow cytometric validation<br>Stem cells<br>References<br>3. Loss of homeostasis<br>Loss of biological balance<br>Tissue adaptation<br>Pathological hypertrophies<br>Heloma<br>Callus formation<br>Liver regeneration<br>References<br>4. Tumor development<br>Characterization of benign and malignant tumors<br>Primary tumor models<br>Classification of tumors<br>Tumor tests<br>Carcinogens<br>Techniques of tumor screening<br>Antitumor agents<br>Benign tumor formation in different tissues and their treatment<br>General steps in tumor formation<br>Benign tumors of major organs<br>References<br>5. Metastasis<br>Historical view of metastasis<br>Spread of tumor cells from local tissue to distant organs<br>Animal cancer models <br>Role of parathymic lymph nodes in metastasis<br>Importance of size distribution of tumor cells in metastasis<br>Metastasis in different organs<br>References<br>Abbreviations</p><p> </p><p> </p><p>

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        Homeostasis - Tumor - Metastasis