<p>I. Anatomy and Pathophysiology of Blinking and Eye Movements<br>Eyelid anatomy and the pathophysiology of blinking<br>Differentiation and morphogenesis of extraocular muscles<br>Extraocular muscle anatomy<br>Extracocular muscle metabolism<br>Extraocular muscles: proprioception and proprioceptors<br>Abnormal eye movements due to disease of the extraocular muscles and their innervation<br>Extraocular muscles: functional assessment in the clinic</p> <p>II. Structure and Function of the Tear Film, Ocular Adnexa, Cornea, and Conjunctiva in Health and Pathogenesis in Disease<br>Meibomian glands and lipid layer<br>Lacrimal gland overview<br>Lacrimal gland hormone regulation<br>Lacrimal gland signaling-neural<br>Lids: Anatomy, pathophysiology, and mucocutaneous junction<br>Ocular surface-overview of electrolyte and fluid transport across the conjunctiva<br>Conjunctival Goblet cells<br>Ocular mucins<br>Tear drainage<br>Cornea overview<br>Corneal epithelium-cell biology and basic science<br>Corneal nerves-anatomy<br>Corneal nerves-function<br>Corneal epithelium-wound healing junctions, attachment to stroma receptors, matrix metalloproteinases, intercellular communications<br>Corneal epithelium-transport and permeability<br>Stem cells of the ocular surface<br>The ocular surface-the surgical treatment for corneal epithelial stem cell deficiency, corneal epithelial defects, and periferal corneal ulcer<br>Refractive surgery<br>Refractive surgery and inlays<br>Contact lenses<br>Imaging of the cornea<br>The corneal stroma<br>Corneal dystrophies<br>Corneal imaging-clinical<br>Corneal scars<br>Corneal endothelium-overview<br>Regulation of corneal endothelial function<br>Regulation of corneal endothelial cell proliferation<br>Artificial cornea<br>Drug delivery to cornea and conjunctiva-esterase- and protease-directed prodrug design<br>Knock-out mice models: cornea, conjunctiva, eyelids, and lacrimal glands<br>Gene therapy</p> <p>III. Immune Regulation of the Cornea and Conjunctiva and Its Dysregulation in Disease<br>Adaptive Immune System and the Eye: Mucosal Immunity<br>Adaptive immune system and the eye: T-cell mediated immunity<br>Innate immune system and the eye<br>Immunoregulatory processes that sustain immune privilege in the eye<br>Immunosupressive and anti-inflammatory molecules that maintain immune previlege of the eye<br>Antigen-presenting cells in the eye and ocular surface<br>Dry eye: An immune-based inflammation<br>Penetrating keratoplasty<br>Immunopathogenesis of HSV Keratitis<br>Immunopathogenesis of Onchocerciasis (River Blindness)<br>Immunopathogenesis of pseudomonas keratitis<br>Immunobiology of acanthomeba karatitis<br>Molecular and cellular mechanisms in allergic conjunctivitis<br>Pathogenesis of fungal keratitis<br>Conjunctiva Immune surveillance<br>Defense mechanisms of tears and ocular surface<br>Corneal epithelium- response to infection<br>Inflammation of the Conjunctiva<br>Concept of Angiogenic Privilege<br>Corneal angiogenesis<br>Avascularity of the cornea</p> <p>IV. Visual Acuity Related to the Cornea and Its Disorders<br>Visual optics: pupil<br>Acuity<br>Contrast sensitivity<br>Astigmatism<br>Vera-Diaz- Myopia<br>Levi-Amblyopia<br>Harb- Hyperopia</p>