Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity

D. Benos, Preface.<br>Structure-Function Relations of Amiloride-Sensitive Sodium Channels:<br>C.M. Fuller, I.I. Ismailov, B.K. Berdiev, V.Gh. Shlyonsky, and D.J. Benos, Mapping Structure/Function Relations in alpha-bENaC.<br>P.M. Snyder, C. Cheng, and M.J. Welsh, Membrane Topology, Subunit Composition, and Stoichiometry of the Epithelial Na⁺ Channel.<br>T.R. Kleyman, I. Ismailov, F. Kosari, B.K. Berdiev, J. Li, and S. Sheng, Subunit Stoichiometry of Heteroligomeric and Homoligomeric Epithelial Sodium Channels.<br>Regulation of Sodium Channels:<br>N. Farman, S. Djelidi, M. Brouard, B. Escoubet, M. Blot-Chabaud, and J.P. Bonvalet, Cell-Specific Expression of EnaC and its Regulation by Aldosterone and Vasopressin in Kidney and Colon.<br>D. Rotin, O. Staub, P. Plant, T. Ishikawa, and L. Schild, Regulation of EnaC by Interacting Proteins and by Ubiquitination.<br>S. Sariban-Sohraby, Role of G-Proteins in the Regulation of Apical Membrane Sodium Permeability by Aldosterone in Epithelia.<br>J.P. Johnson, J.-M. Wang, and R.S. Edinger, The Role of Post-Translational Modifications in the Cellular Mechanism of Aldosterone.<br>J.A. Schafer, L. Li, D. Sun, R.G. Morris, and T.W. Wilborn, Regulation of Amiloride-Sensitive Na⁺ Channels in the Renal Collecting Duct.<br>P.R. Smith, cAMP Mediated Regulation of Amiloride-Sensitive Sodium Channels: Channel Activation or Channel Recruitment?<br>J.K. Bubien, Human Lymphocyte Ionic Conductance.<br>H. Cantiello, Regulatory Aspects of Apx, a Novel Na⁺ Channel with Connections to the Cytoskeleton.<br>Sodium Channels in the Lung:<br>C.R. Talbot, Species Specific Variations in EnaC Expression and Localization in Mammalian Respiratory Epithelium.<br>S. Matalon, M.D. DuVall, and A. Lazrak, Inhibition of Vectorial Na⁺ Transport Across Alveolar Epithelial Cells by Nitrogen-Oxygen Reactive Species.<br>H. O'Brodovich, B. Rafii, A.K. Tanswell, and O. Pitkänen, Induction of Epithelial Sodium Channel Expression and Sodium Transport in Distal Lung Epithelia by Oxygen.<br>Y. Marunaka and N. Niisato, Catecholamine Regulation of Amiloride-Sensitive Na⁺ Transport in the Fetal Rat Alveolar Epithelium.<br>S. Guggino, Cyclic-Nucleotide Gated Cation Channels Contribute to Sodium Absorption in Lung: Role of Non-Selective Cation Channels.<br>Sensory and Mechanical Transduction:<br>M. Driscoll, H.A. Thieringer, S. Sahota, and I. Mano, C. elegans Members of the DEG/EnaC Channel Superfamily: Form and Function.<br>S.C. Kinnamon, B. Lindemann, and T.A. Gilbertson, Amiloride Sensitive Sodium Channels in Taste.<br>Clinical Relevance:<br>D. Benos, The Involvement of Amiloride-Sensitive Na⁺ Channels in Human Genetic Hypertension: Liddle's Syndrome.<br>I.I. Ismailov and B.K. Berdiev, Epithelial Sodium Channels in Cystic Fibrosis.