Veerle Baekelandt,
Evy Lobbestael
Elsevier Science
e druk, 2017
9780128051207
Disease-Modifying Targets in Neurodegenerative Disorders
Paving the Way for Disease-Modifying Therapies
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2017
ISBN13: 9780128051207
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Juridisch
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Levertijd ongeveer 9 werkdagen
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Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies.
This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.
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Inhoudsopgave
<p>1. The multitude of therapeutic targets in neurodegenerative proteinopathies<br>2. Synuclein misfolding as a therapeutic target<br>3. Neuroinflammation as a therapeutic target in neurodegenerative diseases<br>4A. Stem cells in neurodegeneration: mind the gap<br>4B. The potential of stem cells in tackling neurodegenerative diseases<br>5. Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapy<br>6. Parkinson’s disease<br>7. Lewy body dementia<br>8. Frontotemporal dementia<br>9. From huntingtin gene to Huntington’s disease-altering strategies<br>10. Amyotrophic lateral sclerosis: mechanisms and therapeutic strategies</p>
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