Seldin and Giebisch's The Kidney

Volume 1<br>Section I: Epithelial and nonepithelial transport and regulation<br>1. Epithelial cell structure and polarity<br>2. Mechanisms of ion and water transport across cell membranes and epithelia<br>3. Renal ion-translocating ATPases<br>4. Cell volume control<br>5. Solute transport, energy consumption and production in the kidney<br>6. Electrophysiological analysis of transepithelial transport<br>7. Renal ion channels, electrophysiology of transport and channelopathies<br>8. Microvascular permeability and the exchange of water and solutes across microvascular walls<br>9. Renal cilia structure, function, and physiology<br>10. Intercellular junctions and cell–matrix interactions<br>11. Principles of cell signaling<br>12. Scaffolding proteins in transport regulation<br>13. The renin–angiotensin system<br>14. Neural control of renal function<br>15. Eicosanoids and renal function<br>16. Extracellular nucleotides, metabolites, and renal function<br><br>Section II: Structural and functional organization of the kidney<br>17. Structural organization of the mammalian kidney<br>18. Biophysical basis of glomerular filtration<br>19. Glomerular cell biology<br>20. Function of the juxtaglomerular apparatus: control of glomerular hemodynamics and renin secretion<br>21. Vasculature of the kidney cortex and medulla<br>22. The development of the kidney<br>23. Molecular and cellular mechanisms of glomerular capillary development<br><br>Section III: Fluid and electrolyte regulation and dysregulation<br>24. Epithelial Na + channels<br>25. Anion channels<br>26. Physiology and pathophysiology of the NaCl cotransporters in the kidney<br>27. Balance and the pathophysiology of acid–base, fluid, and electrolyte disorders<br>28. Sodium and chloride transport in the proximal tubule<br>29. Mineralocorticoid action in the aldosterone-sensitive distal nephron<br>30. Genetic disorders of renal salt homeostasis and blood pressure<br>31. Pathophysiology of sodium retention and wastage<br>32. Physiology and pathophysiology of hypertension<br>33. Aquaporin water channels in mammalian kidney<br>34. Thirst and vasopressin<br>35. The urine-concentrating mechanism and urea transporters<br>36. Hyponatremia<br>37. Hypernatremic states<br>38. The function and regulation of renal K + channels<br>39. Extrarenal potassium metabolism<br>40. Regulation of K⁺ excretion<br>41. Physiopathology of potassium deficiency<br>42. Clinical disorders of hyperkalemia<br><br>Volume 2<br>Section III: Fluid and electrolyte regulation and dysregulation (contd)<br>43. Intracellular pH homeostasis<br>44. SLC4 sodium-coupled bicarbonate and carbonate transporters<br>45. Anion exchangers of the SLC4 gene family<br>46. Cellular mechanisms of renal tubular acidification<br>47. Renal ammonium ion production and transport<br>48. Clinical syndromes of metabolic alkalosis<br>49. Clinical syndromes of metabolic acidosis<br>50. Respiratory acid–base disorders<br>51. Mechanisms and disorders of magnesium metabolism<br>52. Calcium channels<br>53. The calcium-sensing receptor<br>54. Renal calcium metabolism<br>55. Kidney stones<br>56. Proximal tubular handling of phosphate<br>57. Clinical disturbances of phosphate homeostasis<br>58. Glucose reabsorption in the kidney<br>59. Kidney transport of amino acids and oligopeptides and aminoacidurias<br>60. Renal filtration, transport, and metabolism of albumin and albuminuria<br><br>Section IV: Pathophysiology of renal disease<br>61. Physiologic principles in the clinical evaluation of electrolyte, water, and acid–base disorders<br>62. Acute kidney injury biomarkers<br>63. Pathophysiology of acute kidney injury<br>64. Ischemic renal disease<br>65. Pathophysiology and pathogenesis of diabetic kidney disease<br>66. Autosomal dominant polycystic kidney disease<br>67. Renal physiology and disease in pregnancy<br>68. Glomerular disorders<br>69. Immunologic mechanisms of vasculitis<br>70. Genetic abnormalities in glomerular function<br>71. Mechanisms of drug nephrotoxicity<br>72. Role of proteinuria in the progression of renal disease<br>73. Oxidative stress and signaling in renal physiology and kidney diseases<br>74. Pathogenesis and management of disordered mineral metabolism in patients with chronic kidney disease<br>75. Individualizing the dialysate to address electrolyte disturbances in the dialysis patient<br>76. Mechanisms of allograft rejection<br>77. Homeostasis of solute and water by the transplanted kidney