Direct Nose-to-Brain Drug Delivery

<p>Section I Basic considerations in nose-to-brain drug delivery</p> <p>1. An overview of anatomical and physiological aspects of the nose and the brain</p> <p>Dignesh Khunt and Manju Misra</p> <p>2. Direct transport theory: From the nose to the brain</p> <p>Namdev Dhas, Dattatray Yadav, Ashutosh Singh, Atul Garkal, Ritu Kudarha, Priyanka Bangar, Jignasa Savjani, Chandrakantsing V. Pardeshi, Neha Garg, and Tejal Mehta</p> <p>3. Physicochemical, biopharmaceutical, and practical considerations for efficient nose-to-brain drug delivery</p> <p>Umesh D. Laddha and Amol A. Tagalpallewar</p> <p>Section II Nanotechnology and naso-brain drug delivery</p> <p>4. Nanomedicines for CNS therapy: Fundamental aspects</p> <p>Drashti Desai, Bala Prabhakar, and Pravin Shende</p> <p>5. Nanotechnological advances in direct nose-to-brain drug delivery for neurodegenerative disorders and other neuroailments </p> <p>Rahul Shukla, Ashish Kumar, and S.J.S. Flora</p> <p>6. Surface modification of nanocarriers as a strategy to enhance the direct nose-to-brain drug delivery </p> <p>Chandrakantsing V. Pardeshi and Eliana B. Souto</p> <p>7. Mucoadhesion as a strategy to enhance the direct nose-to-brain drug delivery</p> <p>Mrunal Patil</p> <p>8. Nanoparticles for direct nose-to-brain drug delivery: Implications of targeting approaches</p> <p>Raju O. Sonawane, Yogeshwar Bachhav, Avinash R. Tekade, and Chandrakantsing V. Pardeshi</p> <p>9. Strategies for enhanced direct nose-to-brain drug delivery</p> <p>Yamini Madav and Sarika Wairkar</p> <p>Section III Carriers for direct nose-to-brain drug delivery</p> <p>10. Particulate carriers for nose-to-brain delivery</p> <p>Shiv Bahadur and Kamla Pathak</p> <p>11. Vesicular carriers for direct nose-to-brain drug delivery</p> <p>Prashant K. Deshmukh, Swapnil N. Jain, Pravin O. Patil, and Chandrakantsing V. Pardeshi</p> <p>12. Gel-based delivery of neurotherapeutics via naso-brain pathways</p> <p>Hitendra S. Mahajan and Payal H. Patil</p> <p>Section IV Applications of direct nose-to-brain delivery</p> <p>13. Applications of direct nose-to-brain drug delivery in medicine and pharmacy</p> <p>Ganesh B. Shevalkar, Mahendra K. Prajapati, Rohan V. Pai, and Kamlesh D. Mali</p> <p>14. Applications of direct nose-to-brain drug delivery in biomedicine, biotechnology, tissue engineering, and immunology</p> <p>Sanjay B. Patil</p> <p>15. Diagnostic and theranostic intranasal nanointerventions for brain diseases</p> <p>Prashant Upadhaya, Sreeranjini Pulakkat, and Vandana Patravale</p> <p>16. Nose-to-brain delivery of biologics and stem cells</p> <p>Mukta Agrawal, Aditya Narayan Konwar, Amit Alexander, and Vivek Borse</p> <p>17. Applications of nose-to-brain delivery in nanodiagnosis and nanotherapy of neurodegenerative disorders</p> <p>Abhijeet Kulkarni, Mahesh Shinde, Gaurav Sonawane, Hitesh Raotole, Rohit Pande, and Chandrakantsing V. Pardeshi</p> <p>18. Intranasal gene therapy for the treatment of neurological disorders</p> <p>Namdev Dhas, Tejal Mehta, Shilpa Sharma, Atul Garkal, Dattatray Yadav, Kartik Hariharan, Babeeta Shamjetshabam, Shubham Khot, Ritu Kudarha, Priyanka Bangar, Gajanan Arbade, and Pratap Kalyankar</p> <p>19. Potential of naso-brain drug delivery in glioblastoma therapy</p> <p>Amarjitsing Rajput, Nikunj Tandel, Swapnil Borse, and Shital Butani</p> <p>20. Nose-to-brain delivery of antiretroviral drugs against NeuroAIDS</p> <p>Kailas K. Moravkar, Devanshi S. Shah, Durgesh K. Jha, Purnima D. Amin, and Sanjay J. Surana</p> <p>Section V Technological advances for effective drug administration</p> <p>21. A technology overview on advanced drug administration devices for effective nose-to-brain delivery</p> <p>Sadhana R. Shahi and Chandrakantsing V. Pardeshi</p> <p>Section VI Evaluation of direct nose-to-brain drug delivery</p> <p>22. Experimental models for evaluation of direct nose-to-brain drug delivery</p> <p>Vinit V. Agnihotri, Ashish P. Gorle, Chandrakantsing V. Pardeshi, and Sanjay J. Surana</p> <p>23. Quantitative and qualitative analysis of direct nose-to-brain drug delivery</p> <p>Veena S. Belgamwar, Vidyadevi T. Bhoyar, Sagar Trivedi, and Chandrakantsing V. Pardeshi</p> <p>Section VII Toxicity and regulatory aspects</p> <p>24. Toxicity aspects: Crucial obstacles to clinical translation of nanomedicines</p> <p>Vikas Bansal, Sameer S. Katiyar, and Chander Parkash Dora</p> <p>25. Nose-to-brain drug delivery: Regulatory aspects, clinical trials, patents, and future perspectives</p> <p>Abhijeet Pandey, Ajinkya Nikam, Shreya Basavraj, Sadhana Mutalik, Divya Gopalan, Sanjay Kulkarni, Bharat Padya, Gasper Fernandes, and Srinivas Mutalik</p>