Anti-Aging Pharmacology

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Paperback, blz. | Engels
Elsevier Science | e druk, 2022
ISBN13: 9780128236796
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Elsevier Science e druk, 2022 9780128236796
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Samenvatting

**Association of American Publishers (AAP) PROSE Award Finalist in Clinical Medicine, 2024**

Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm.

This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice.

Specificaties

ISBN13:9780128236796
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>SECTION I. Conceptual and Methodological Backgrounds <br>1. Can Aging be Cured as a Disease?<br>2. Geroscience Conceipt<br>3. Mechanistic Pathways of Aging<br>4. Biomarkers of Aging Rate<br>5. Artificial Intelligence-Based Approach in Anti-Aging Pharmacology<br>6. Big Data Approach<br>7. OMICs Approaches</p> <p>SECTION II. Basic Classes of Anti-Aging Drugs<br>8. Antioxidant Paradox<br>9. Melatonin<br>10. Calorie Restriction Mimetics<br>11. Metformin<br>12. Rapamycin and rapalogs<br>13. Nonsteroidal Anti-Inflammatory Drugs<br>14. Statins<br>15. Senolytics<br>16. Epigenetic Drugs<br>17. Sirtuin Activating Compounds<br>18. Autophagy Inducers<br>19. Mitophagy Modulators<br>20. Telomerase Activators</p> <p>SECTION III. Phytochemicals<br>21. Resveratrol<br>22. Curcumin<br>23. Quercetin<br>24. Genistein<br>25. Epigallocatechin Gallate<br>26. Berberine<br>27. Nanodelivery of phytobioactive compounds: a promise in anti-aging medicine</p> <p>SECTION IV. Outcomes and Concluding Thoughts<br>28. Ethical perspectives on advances in biogerontology<br>29. Implications for Public Health Policy<br>30. The Business of Anti-Aging Science</p>

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        Anti-Aging Pharmacology