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Exosome Communication

Advances in Research and Therapeutics for Health and Disease

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2024
ISBN13: 9780443290527
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Elsevier Science e druk, 2024 9780443290527
€ 225,39
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Samenvatting

Exosome Communication: Advances in Research and Therapeutics for Health and Disease serves as a crucial reference for pharmaceutical scientists, focusing on the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering significant advantages over traditional drug delivery systems such as liposomes and polymeric nanoparticles, due to their nonimmunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for isolation and characterization. This book also addresses critical considerations like quality control, heterogeneity reduction, regulatory and ethical aspects, clinical trials, and scale-up manufacturing.

Specificaties

ISBN13:9780443290527
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. Introduction: History and Development of Exosomes Nanovesicles<br>2. Exploring Extracellular Vesicles: Understanding Exosomes and Beyond<br>3. Exosome Isolation Techniques: Methods, Protocols, and Best Practices<br>4. Improving Cargo Loading and Release Strategies for Exosomes Nanovesicles<br>5. Exosome Characterization Techniques, Composition Analysis and Contents of Exosomes Nanovesicles: Methods and Interpretation<br>6. Quality Control, Minimizing Heterogeneity and Enhancing Yield in Exosome Isolation and Production<br>7. Inhibition of Cell-Cell Communication in Exosomes<br>8. Modifications of Exosomes Nanovesicles for Targeted drug delivery<br>9. Challenges for the Development of Exosome Nanovesicle-Based Formulations for Drug Delivery and Assessing Toxicity<br>10. Diagnostic Potential and Biomarkers Potential of Exosome Nanovesicles<br>11. Exosomes in Immunology<br>12. Exosomes in Protein and Peptide Delivery<br>13. Exosomes Nanovesicles in Antigen-Specific Antibody Delivery, Gene Delivery, and Vaccine Delivery<br>14. Theranostic Potential of Exosomes in Neurodegenerative Diseases<br>15. Exosomes in Cancer Therapeutic Delivery<br>16. Potential Role of Microbial-derived Exosomes in Human Health and Diseases<br>17. Current Applications of New Generations of Exosomes Nanovesicles<br>18. Clinical Trials and Translational Research in Exosome Nanovesicle Therapeutics<br>19. Scale-up and Manufacturing of Exosome-based Therapeutics<br>20. Regulatory and Ethical Considerations in Exosome-Based Therapeutics

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€ 225,39
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        Exosome Communication