I. Blood and Blood Vessel Interaction.- 1. Blood Rheology Interpreted through the Flow Properties of the Red Cell.- 1.1. Macroscopic Rheology and Tube Flow of Human Blood.- 1.2. Red Cell Interactions in Low Flow States.- 1.3. Rheology of Red Blood Cell Membrane.- 1.4. Pressure-Flow Relationships in the in Vivo Microcirculation.- 2. Methods for the Investigation of the Microcirculation.- 2.1. Noninvasive Measurement of Compliance of Small Arteries.- 2.3. A Method of Determining Resistances from Pressure-Flow Measurements with Microvascular Occlusions.- 2.4. Image Degradation in Magnification Radiology by Phase Shift.- 2.5. A New Low-Density, Nonaggregating Microsphere for Microcirculation Research.- 2.6. Development of an Index for Evaluating the Response of the Microvasculature in C3H Mice to Various Vasoactive Drugs.- 2.7. A Microscope Laser Doppler Anemometry (LDA) System for Measurement of Flow Velocity and Velocity Profiles in Vivo in the Vessels of the Microvascular System.- 2.8. A Video System for Measuring the Blood Flow Velocity in Microvessels.- 2.9. New Methods of Measuring the Different Rheological Parameters in Blood.- 2.10. Internal Tissue Heat during in Vivo Transillumination with Fused Quartz and Borosilicate Glass Rods.- 3. Red Cell Interactions with the Microcirculation.- 3.1 Red Blood Cell Velocity Profiles in Arterioles and Venules of the Rabbit Omentum.- 3.2 Analysis of Red Blood Cell Velocity Distribution in Human Nailfold Capillaries.- 3.3 In Vivo Study of “Apparent Viscosity” and Vessel Wall Shear Stress in Cat Mesentery.- 3.4. Flow Velocities of Red Blood Cells and Their Suspending Medium Measured in Glass Capillaries Using the Photometric Dual-Slit Method.- 3.5. A New On-Line Method of Measuring High Flow Speeds in Microscopic Vessels by a Dual Video Camera Technique.- 3.6. Blood Cells in an Annular Vortex.- 3.7. Geometry of the Fetal Erythrocyte and Its Relation to Osmotic Fragility.- 3.8. Electrochemical and Mechanical Factors in Red Cell Interactions.- 3.9. Role of the Erythrocyte Surface Charge in the Microcirculation.- 3.10. Velocity-Dependent Resistance Behavior of Erythrocytes in Capillary Pores and Membrane Elasticity.- 3.11. Effects of Altered Red Cell Deformability on Capillary Flow Resistance.- 3.12. Effect of Heat-Traumatized Blood on Microcirculatory Dynamics.- 3.13. Effect of Heat-Induced Spherocytes on Intrahepatic Microcirculation.- 3.14. Locomotion and Chemotaxis of Human Neutrophils.- 3.15. Leukocyte Adhesiveness as Influenced by Blood Velocity.- 3.16. Erythrocyte and Platelet Geometry: Comparative Quantitative Estimates by Static Microscopic and Rheo Optical Determinations.- 3.17. Erythrocyte Sedimentation of Human Blood at Varying Shear Rates.- 3.18. Erythrocyte Sedimentation Rate and “a Sedimentimeter”.- 3.19. Osmotic Fragility Curves as Frequency Distributions.- 3.20. Psychosomatic Pain and Elevation of Blood Viscosity Factors.- 3.21. Blood Viscosity Factors in Diagnostic and Preventive Medicine.- 3.22. Rheological Properties of Sickled Red Cells in the Microcirculation.- 3.23. Some Effects of Tube Diameter on Oscillatory Blood Flow.- 4. Blood Vessel Structure.- 4.1. An Intracellular Tubular System in Capillary Endothelium.- 4.2. Observations of Pulmonary Capillary Endothelial Junctions Studied by the Freeze-Fracture/Etch Technique.- 4.3. On the Fine Structure of the Arteriovenous Anastomoses of the Rabbit Ear.- 4.4. Scanning Electron Microscopic Evaluation of Rat Femoral Artery Endothelium Following Microvascular Surgery.- 4.5. On the Organ Specificity of Microvessels: Heterogeneity of Arteriolar Metabolism.- 5. Microcirculatory Flow Patterns.- 5.1. The Natural History of Microcirculation.- 5.2. Increased Capillary Flow Rate of Erythrocytes in Hyperosmolar Human Blood by the Addition of Pentoxifylline.- 5.3. Measurement of Arteriovenous Circulation Time and Volume Flow in the Human Retin.- 5.4. Microcirculation of the Terminal Gill Lamellae in the Freshwater Goldfish (Carassius auratus) and the Marine Gobie (Lythrypnus dalli).- 5.5. Flow Patterns in the Capillary Bed of Rat Skeletal Muscle at Rest and after Repetitive Tetanic Stimulation.- 5.6. Transcapillary Pressure Gradients and Coefficients during Isotonic Mannitol Loads: Evidence for Capillary Intermittency.- Segmental Resistances in the Microcirculation of the Mesentery and Omentum.- 6. Formed Elements of the Blood Platelets, and Thrombosis.- 6.1. Platelets in Response to the Injury in the Microcirculation- A Review.- 6.2. Double Labeling of Platelets with 5 1 Cr and [14C]Serotonin.- 6.3. Inhibition of Platelet Function by Angiographic Contrast Media.- 6.4. Electronic Particle Size Measurement of Platelet Aggregates.- 6.5. Videomicroscopy and Videodensitometry of Platelet Aggregation under Controlled Conditions of Blood Flow and ADP Convective Diffusion.- 6.6. Effects of Agar on Platelet Aggregation.- 6.7. Effects of pH and PC02 on ADP-Induced Platelet Sphering and Aggregation for Human and Rabbit Citrated Platelet-Rich Plasma.- 6.8. Effect of a New Potent Inhibitor of Platelet Aggregation (BL-3459) on Experimental Thrombosis.- 6.9. Hematological Effects of a Splenic Extract.- 6.10. Inhibition of ADP-Induced Platelet Aggregation by Canine Spleen Alkaline Phosphatase.- 6.11. Effect of Diflunisal, a Novel Salicylate, on Platelet Function and Blood Coagulation.- 6.12. Polyphloretin Phosphate, an Inhibitor of Platelet Function.- 6.13. Platelet Aggregation and Particulate Microembolization during Cardiac Operations.- 6.14. Growth Patterns of Platelet Thrombi and Their Relationship to Microemboli.- 6.15. Effect of Hormonal Contraceptives on Electrically Induced Thrombosis Times in Rats.- 6.16. Interaction between Platelet Thrombi and the Vessel Wall.- Platelet and Fibrinogen Preservation in Intraoperative Autotransfusion.- 6.18. Effect of Gliclazide on Irradiation-Induced Experimental Atheromatosis.- 6.19. A Diagnostic Sign in the Small Blood Vessels of the Conjunctiva in Arteriosclerosis.- 6.20. Ventilatory Dysfunction after Long-Lasting Intravascular Platelet Aggregation.- 6.21. Studies on Platelet and Red Cell Survival after Cardiopulmonary Bypass (CPB) without Blood Filter.- 6.22. Osmotic Fragilities and the Kalmedic Fragiligraph Model D-3.- 7. Lymphatics.- 7.1. Electron Microscopic Studies of the Lymphatic Endothelium in Lymphangiectasia of the Small Intestine.- 7.2. Microcirculation of the Human Lymph Node.- 7.3. Quantitation of Blood Flow to and Lymph Output from Single Lymph Nodes.- 7.4. Flow of Albumin through Renal Lymph: The Total Clearance.- 7.5. Contributions to Regional Tissue Lymph by the Local Lymph Node in Sheep.- 7.6. Effects of Chemical and Physical Conditions on the Flow Rate of Intestinal Lymphatics.- 7.7. Lymph Flow Augmentation Secondary to Rises in Serum Calcium.- 7.8. Transport of Air via Lymph Vessels in Experimentally Induced Emphysema.- 8. Neurohumoral Control of Blood Vessels.- 8.1. Integrated Response of the Microvasculature to Stimulation of the CNS in the Rat.- 8.2. Comparative Studies on Adrenergic Receptors in Different Rat Blood Vessels.- 8.3. Adrenergic Innervation of the Blood Vessels of the Spinal Cord of the Cat.- 8.4. Effect of CO2 on the ?-Adrenergic Receptor: A Control Mechanism for Tissue Blood Flow.- 8.5. Effects of a and ? Blockade on Oxygen Supply to Rat Brain and Muscle.- 8.6. Evidence for Increased ?-Adrenergic Receptor Function in Isolated Perfused Carotid Artery from Cold- Acclimated Rabbits.- 8.7. Catecholamines in Low Flow States.- 8.8. Effect of Steroids on Human Venous Smooth Muscle in Vivo and in Vitro.- 8.9. Direct Contractile and Metabolic Actions of Nitroglycerine on the Heart.- II. Blood Flow in Special Tissues.- 9. Pulmonary Circulation.- 9.1. Biomicroscopic Investigations on the Connection between the Capillary Bed and the Larger Vessels of the Lungs of Some Reptiles.- 9.2. Pulmonary Capillary Filtration Coefficient and Permeability to HRP in Dogs.- 9.3. Weight vs. Electrode Detection of Outflow Response of Isolated Perfused Dog Lung to Osmotic Solutes.- 9.4. Pulmonary Extraction of 5-Hydroxytryptamine: Antagonism by Imipramine ill the Intact Anima.- 9.5. Pulmonary Microcirculation during Lethal Hypovolemia in the Cat.- 10. Myocardial Blood Flow.- 10.1. Microcirculation in the Ventricle of the Dog and Turtle.- 10.2. Temporal Heterogeneity of Myocardial Perfusion.- 10.3. A New Model for Assessing Myocardial Function.- 10.4. Washout and Washin Behavior of the Myocardial Extracellular Space: Significance for Evaluation of Capillary Permeability and Interstitial Space Concentrations of Metabolites.- 10.5.. Changes in Coronary Vessels Induced by Repeated Hypothalamic Stimulation.- 10.6. Microangiographic Reevaluation of the Human Intramyocardial Vasculature.- 10.7. Predictive Value of Myocardial Scanning for Coronary Artery Bypass Surgery.- 10.8. Myocardial Perfusion Defects in Patients with Valvular Heart Disease.- 10.9. Myocardial Perfusion Abnormalities in Patients with Cardiomyopathy.- 10.10. Fluorescence Microscopic Demonstration of Localized Myocardial Ischemia.- 10.11. Oxygen Utilization and Coronary Vascular Reserve in the Ischemic Myocardium Following Acute Coronary Occlusion in the Dog.- 10.12. Reduction of Myocardial Infarct Volume by Methylprednisolone.- 10.13. Pathological Anatomy of the Subendocardial Vasculature after Anoxic Cardiac Arrest.- 10.14. Metabolic Response of the Heart to Ischemic Arrest during Cardiac Surgery: Assessment by Means of Intramyocardial Carbon Dioxide Tension.- 10.15. Prevention of “Stone Heart” after Anoxic Cardiac Arrest.- 10.16. Effect of Aprotinin on Levels of Adenine Nucleotides and Nucleosides in Postischemic Myocardium in Dogs.- 11. The Splanchnic Circulation.- 11.1. Microvascular Pressures in Innervated Rat Intestinal Muscle and Mucosa.- 11.2. Microsphere Distribution in Revascularized Intestine.- 11.3. Microcirculation from the Villus to the Liver.- 11.4. Biomicroscopic Studies of Microcirculation of the Rat Intestine.- 11.5. Filtration Coefficients of Single Capillaries in Rat Intestinal Muscle.- 11.6. Role of Collagenase in Capillarization of Hepatic Sinusoids.- 11.7. Effect of Diminished P50 on Intrahepatic Oxygen Tension as Measured in Bile.- 11.8. Phenomenon of Intrahepatic Microcirculatory Redistribution.- 11.9. A Flow Model of the Liver and the Microcirculatory Hepatic Unit.- 11.10. The Isolated Perfused Liver as a Model for the Study of Disseminated Intravascular Coagulation. I. Effects of Trasylol, Heparin, and Acetylsalicylic Acid.- 11.11. Effects of Acute Hemorrhage and Carotid Artery Occlusion on Blood Flow and Its Distribution in the Wall of the Gastrointestinal Tract.- 11.12. Effects of Arterial Pressure Variation on Microvascular Pressure Distribution in the Mesentery during Intravenous Infusion of Norepinephrine.- 11.13. Mechanism of Escape from Norepinephrine Vasoconstriction in the Intestinal Circulation.- 11.14. In Vivo Study of the Effects of Acetaminophen(Paracetamol) on the Hepatic Mic~ocirculation.- 11.15. In Vivo and Electron Microscopic Study of the Splenic Microvascular System.- 11.16. Experimental and Theoretical Investigations on Intrasplenic Microcirculation in Rats.- 11.17. Neural Influences in the Humoral Regulation of the Splenic Microvasculature.- 11.18. The pH of Splenic Microcirculation.- 11.19. Specific Erythropoietin-Related Changes in the Splenic Microcirculation during Hypoxic and Posthypoxic Polycythemia: Comparison with Other Organs.- 12. Blood Flow in Skeletal Muscle.- 12.1. Microcirculation in Skeletal Muscle: Geometry of the Capillary Vascular Network.- 12.2. Regions of Preferential Blood Flow in Skeletal Muscle.- 12.3. Distribution of Blood Flow in Microcirculation in Cat Tenuissimus Muscle.- 12.4. Apparent Distribution of Capillary and Shunt Flow in Canine Skeletal Muscle.- 12.5. The Microvascular Bed and Capillary Surface Area in Rat Extensor Hallucis Proprius Muscle.- 12.6. Kinetics of Red Cell and Plasma Washout from the Vascular Bed of Skeletal Muscle.- 12.7. Blood Oxygen Saturation Determination in Frozen Dog Gracilis Muscle.- 12.8. Functional Arteriolar Vasodilatation in Striated Muscle.- 12.9. Blood Flow Changes Due to Compression in Contracting Muscles.- 12.10. Changes in the Capillary Density and Reactivity of the Vascular Bed in Chronically Stimulated Fast Muscles.- 12.11. Skeletal Muscle Vascular Volume Changes with Increased Venous Pressure.- 12.12. Flow Improvement in the Vasodilated Skeletal Muscle of the Dog by Slow Defibrinogenation with Arvin.- 13. Microcirculation in Other Tissues.- 13.1. Quantitative Studies of Brain Microcirculation Using
Quasilinearization Techniques.- 13.2. Microangiography and Tryptan Blue Fluorescence Study of Cardiac-Arrested Dog Brain.- 13.3. Pharmacological Control of O2 Autoregulation in Brain Tissue.- 13.4. “Migraine”-Studies on Intravital Microcirculation: Synergism of the Action between Serotonin and Bradykinin on the Encephalic Circulation System.- 13.5. Oxygen Supply to the Spinal Cord and Its Autoregulation.- 13.6. Regional Changes in Pial Blood Supply Induced by Hypothalamic Stimulation.- 13.7. Influence of Aminophylline on the Cerebral Blood Circulation and CSF Pressure.- 13.8. Electrocorticographic and Pial Microvascular .Hemodynamic Correlations during Pentylenetetrazol- and Enflurane- Induced Seizures in the Cat.- 13.9. Regional Blood Flow in Normal Skin and the Pedicle Skin Thp.- 13.10. Microvasculature in Open Cremaster.- 13.11. Childhood Asthma and Peptic Ulcer: Studies of the Lip Capilmries.- 13.12. Effects of Perfusion Pressure on Focal Ischemia in the Retina: Experimental and Clinical Studies.