Bioarrays

Foreword: Sir Edwin Southern

Introduction: Krishnarao Appasani

Section 1: BioArray Technology Platforms

Chapter 1: The Investigation of Tumour Metastasis using cDNA Microarrays
David Murray, Francesco Gorreta, Geraldine Grant, Vikas Chandhoke and Susan McDonnell

Chapter 2: From tissue samples to tumor markers
Dirce Maria Carraro, Helena Paula Brentani, Fernando Augusto Soares,
Luiz Fernando Lima Reis and Ricardo Renzo Brentani

Charter 3: Experimental design for assessment of gene expression changes using microarrays. Answers are easy, is asking the right question difficult?
Marcia V. Fournier, Paulo da Costa Carvalho, David D. Magee and Maria da Gloria Costa Carvalho

Chapter 4: From Microarrays to Gene Networks
Hasan H. Otu and Towia A. Liberman

Section 2: Biomarkers and Clinical Genomics

Charter 5: Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivity
Williams, Amanda J.; Hagan, Kevin W.; Culp, Steve G.; Medd, Amy; Mrzljak, Ladislav; Defay, Tom R., and Mallamaci, Michael A.

Chapter 6: Genomics to identify biomarkers of normal brain aging
Loubna Erraji-Benchekroun, Victoria Arango, John J. Mann, and Mark D. Underwood

Chapter 7: Gene expression profiling for biomarker discovery
Kazuhiko Uchida

Chapter 8: Array-based Comparative Genomic Hybdidization: applications in cancer and tuberculosis
Murali D. Bashyam and Seyed E. Hasnain

Chapter 9: The regional specialization of endothelial cell as revealed by genomic analysis
Jen-Tsan Ashley Chi, Zhen Wang and Anil Potti

Section 3: Biomarker Identification Using Clinical proteomics and Glycomics

Chapter 10: Identification of target antigens in CNS inflammation by protein array technique
Sabine Cepok, Bernhard Hemmer, Konrad Büssow

Chapter 11: Differential Protein Expressio, Protein profiles of Human Gliomas and Clinical Implications
.Ravi Sirdeshmukh, VaniSantosh and Anusha Srikanth

Chapter 12: Antibody-Based Microarrays: From Focussed Assays to Proteome-Scale Analysis
Christer Wingren and Carl AK Borrebaeck

Chapter 13: GlycoProfiling by DNA-Sequencer Aided-Fluorophore Assisted Carbohydrate Electrophoresis: new opportunities in diagnosing and following disease
Wouter Laroy and Roland Contreras

Chapter 14: A high-throughput biochip platform for constructing carbohydrate microarrays
Denong Wang, Dhaval Shah , Ruobing Wang, Shaoyi Liu, Aili Wang, Xiaoyuan Xu,
Brian J. Trummer, Chao Deng and Rong Chen

Section 4: Emerging Technologies in Diagnostics

Chapter 15: Microarrays and blood diagnostics
Juraj Petrik and Janine Scott Robb

Chapter 16: Lab-on-a-chip devices for cellular arrays based on dielectrophoresis
ROBERTO GAMBARI, MONICA BORGATTI, ENRICA FABBRI, RICCARDO GAVIOLI, CINZIA FORTINI, CLAUDIO NASTRUZZI, LUIGI ALTOMARE, MELANIE ABONNEC, NICOLÒ MANARESI, GIANNI MEDORO, ALDO ROMANI, MARCO TARTAGNI AND ROBERTO GUERRIERI

Chapter 17: Genetic Disorders and Approaches to their Prevention
G. R. Chandak and J. Hemavathi