Strategies for Immunointerventions in Dermatology

1 Basic Aspects.- A Rational Approach to Immune Intervention.- Skin as an Immunocompetent Organ in Health and Disease.- 2 Immunosuppressive and Antiinflammatory Compounds.- Cyclosporin A.- Rapamycin.- FK-506/Tacrolimus.- Low-Dose Methotrexate: An Immunomodifying Therapeutic Strategy for Dermatologie Diseases.- Leflunomide.- Fusion Toxins.- Dermatological Phototherapy: A Prime Example of Ultraviolet Radiation-Induced Immunointervention.- Cytokines with Immunosuppressive Capacities.- Extracorporeal Photochemotherapy.- Glucocorticosteroids.- High-Dose Intravenous Immunoglobulins.- 3 Immunostimulatory Substances and Vaccination Therapies.- Interferon-a Therapy in Dermatology.- Tumor Necrosis Factors.- Cytokines and Cytokine Gene Transfer in Cancer Treatment.- Development of a DNA Vaccine Against Malignant Melanoma.- Low Molecular Weight Cytokine Inducers.- 4 Clinical Aspects of Immunosuppression and Immunostimulation.- 4.1 Dermatoses Treated with Immunosuppressives 217.- Autoimmune Bullous Diseases.- Rheumatic Disease Group.- Atopic Dermatitis.- Psoriasis - Mediation of Skin Phenotype by Circulatory Pathogenic T Lymphocytes.- Vasculitis Allergica.- Contact Dermatitis.- Pyoderma Gangrenosum.- 4.2 Dermatoses Treated with Immunostimulatory Drugs andVaccination Therapies 293.- 4.2.1 Infections 293.- Viral Infections: Human Papillomavirus Infections Treated with Immunostimulatory Drugs and Vaccination Therapies.- Immunostimulation and Vaccination Therapy of Human Immunodeficiency Virus Infection.- Cytokine Therapy and Vaccination in Tropical Diseases Leishmaniasis and Leprosy.- 4.2.2 Neoplasms321.- Cutaneous Lymphomas.- Non-melanoma Skin Cancer.- Therapy of Kaposi’s Sarcoma.- 4.2.3S trategies for Immunointervention in Malignant Melanoma357.- Adjuvant Melanoma Therapy.- Cytokine-Based Treatments for Advanced Melanoma.- Gene Therapy: A New Perspective for the Treatment of Malignant.- Topical Immunotherapy of Malignant Melanoma.- Vaccination with Dendritic Cells — A Specific Immunomodulatory Approach for the Treatment of Malignant Melanoma.