Protein Synthesis and Targeting in Yeast

Mrna Stability and Translation.- 1: Identification of the cis-acting sequences and trans-acting factors involved in nonsense-mediated mRNA decay.- 2: RNA14 and RNA15, two proteins regulating mRNA stability in Saccharomyces cerevisiae.- 3: Translational control in Saccharomyces cerevisiae studies in vivo and in vitro.- The Ribosome.- 4: Thoughts on the regulation of ribosome synthesis in Saccharomyces cerevisiae.- 5: Regulation of ribosomal protein synthesis in yeasts (Saccharomyces and Kluyveromyces).- 6: The evolution of ribosomal proteins and yeast.- 7: The acidic ribosomal proteins and the control of protein synthesis in yeast.- Translational Fidelity.- 8: SUP35 and SUP45 genes code for ribosome-bound proteins involved in the control of translational fidelity in yeast.- 9: Mutations affecting translational accuracy in yeast.- 10: Dosage-dependent modifiers of psi’-dependent omnipotent suppression in yeast.- 11: Aberrant mRNA decoding by the dimorphic yeast Candida albicans.- Translation Factors.- 12: Effect of initiation factor eIF-5A depletion on cell proliferation and protein synthesis.- 13: Analysis of the genes encoding eIF-4A from yeast.- 14: Uncharged tRNA and derepression of the general amino acid control: autoregulation of yeast lysyl-tRNA synthetase.- Translation in the Mitochondrion.- 15: Positive control of translation in organellar genetic systems.- 16: Translation in yeast mitochondria.- 17: Yeast mitochondrial translation: nuclear genes involved in the expression of the mitochondrial genome.- Mitochondrial Import and Sorting.- 18: Early events in protein import into mitochondria.- 19: Targeting pathways to the mitochondrial inner membrane.- 20: Intra-mitochondrial sorting of precursor proteins.- 21: Genetic characterization of the intermembrane spacesorting domains of yeast cytochrome b2.- 22: Mitochondrial import of cytochrome C.- Nuclear Transport.- 23: Using yeast to study exchange of macromolecules between the cytoplasm and the nucleus..- 24: Nucleocytoplasmic transport in ribosome biogenesis.- 25: Approaches towards a genetic analysis of the nuclear pore complex in yeast.- Targeting to the Endoplasmic Reticulum and Beyond.- 26: The SRP-dependent protein targeting pathway in Saccharomyces cerevisiae.- 27: Similarities between Scerevisiae Sec 61p and E. coli SecY suggest a common origin for protein translocases of the eukaryotic ER and the bactenal plasma membrane.- 28: ATP transport into yeast ER is a prerequisite for preprotein transfer across the ER membrane.- 29: Cross-linking signal sequences to components of yeast microsomes.- 30: The nucleotide cycle of SEC4 is important for its function in vesicular transport.- 31: Vacuolar protein sorting in yeast.- 32: Eukaryotic MDR1/P-glycoprotein homologues: unconventional secretion processes mediated by a growing family of ATP-dependent membrane translocators.- Intracellular Protein Folding.- 33: The role of protein disulfide isomerase in yeast.- 34: Novel chaperone-like pro-sequences allow secretion of recombinant human insulin-like growth factor-1 from yeast.- 35: mRNA translation and protein folding in vivo.- Protein Splicing and Degradation.- 36: Protein splicing of yeast TFP1: evidence for a new class of mobile genetic elements.- 37: Ubiquitin-dependent protein degradation.- 38: The TIF463A and TIF463B genes encode the large subunits of the yeast cap binding protein complex.