Endoplasmic Reticulum Stress in Health and Disease

<p><p>Preface</p><p>Part I: Cellular responses to ER stress</p><p>1.      Biology of the endoplasmic reticulum.  </p><p>2.      A tight-knit group: protein glycosylation, endoplasmic reticulum stress and the unfolded protein response. </p><p>3.      ER stress signaling pathways in cell survival and death. </p><p>4.      endoplasmic reticulum-mitochondria connections, calcium cross-talk and cell fate: a closer inspection. </p><p>5.      ER stress and upr through dysregulated er ca²⁺ homeostasis and signaling. </p><p>6.      Regulation of ER stress responses by micrornas. </p><p>7.      ER stress as modulator of autophagy pathways. </p><p>8.      physiological ER stress: the model of insulin-secreting pancreatic β-cells. </p><p>Part II: ER stress in physiological & pathological conditions</p><p>9.      Pathological ER stress in b cells. </p><p>10.  Endoplasmic reticulum stress and the unfolded protein response in lipid metabolism and obesity. </p><p>11.  ER stress and inflammation. </p><p>12.  ER stress in intestinal inflammatory disease. </p><p>13.  Role of ER stress in dysfunction of the nervous system. </p><p>14.  Endoplasmic reticulum (ER) stress in amyotrophic lateral sclerosis (als). </p><p>15.  Cardiovascular disease and endoplasmic reticulum stress. </p><p>16.  Signaling the unfolded protein response in cancer. </p><p>17.  Upr activation in cancer cells: a double-edged sword. </p><p>18.    Contribution of ER stress to immunogenic cancer cell death. </p><p>19.   current advances in ER stress intervention therapies. </p><p>Index</p><p>