Helicobacter pylori Infection

Introduction. 1. Historical and microbiological perspectives; C.S. Goodwin. Epidemiology. 2. Geographical distribution and association with gastric cancer; D. Forman, P. Webb. 3. Natural history and mode of transmission; M. Mendall. Pathophysiology. 4. Pathogenesis of infections due to persistent bacteria at mucosal surfaces; M.J. Blaser. 5. Host responses; J.E. Crabtree, J.I. Wyatt. Role of Peptic Ulcer Disease. 6. Acid secretion; J. Calam. 7. Mucosal defence; P.M. Goggin, T.C. Northfield. 8. Overview; G.N.J. Tytgat. 9. The precancer-cancer sequence; T. Levine, A.B. Price. Role in Gastric Cancer. 10. Biochemical aspects; G. Sobala. Diagnosis. 11. Histological diagnosis; M.F. Dixon. 12. Urea breath tests; G.D. Bell. 14. Serology; D.G. Newell, A.R. Stacey. Treatment. 15. Drug regimens; A.T.R. Axon. 16. Vaccination: possibilities and probabilities; Minhu Chen, A. Lee. Conclusion. 17. Conceptual evolution from gastritis, to peptic ulcer and gastric cancer, to `cystitis of the stomach' and, finally, to a smallpox equivalent; D.Y. Graham. Index.